Health Benefits of Melatonin. It is primarily recommended to supplement with melatonin for supporting healthy sleep.* It may also be a useful supplement for daytime stress management, among a variety of other beneficial properties.* Clinical research suggests the benefits of melatonin supplementation may include: • Supports proper sleep cycles and circadian rhythms* Supports healthy growth hormone production* • May help with falling asleep and jet lag* • Supports relaxation and calmness* Supports immune function* What is Melatonin? TonicSea offers three convenient forms of melatonin: Melatonin Pro (capsule), Melatonin TR Pro (time release) and Melatonin Liquid. Melatonin is a hormone secreted by the pineal gland in the brain that is used by the body to help regulate its internal body clock and induce sleep. The body also produces melatonin through metabolism of the neurotransmitter serotonin.

MELATONIN FORMULAS Melatonin secretion is regulated by hormone/neurotransmitter norepinephrine. Exposure to light environments (such as daylight) reduces melatonin synthesis by stopping stimulation of norepinephrine, whereas exposure to dark environments does the opposite. Thus, it is easier for people to fall asleep when it’s dark outside as opposed to bright, sunny times of the day. This is why normal circadian rhythms are imperative for proper melatonin production and a healthy sleep cycle. Night shift workers may struggle to sleep for more than several hours per day as their body is essentially on an inverse schedule in terms of normal circadian rhythms. Melatonin: How it Works & Clinical Research. There are a host of benefits that arise from supplementing with melatonin due to its ability to support healthy sleep patterns.* Research shows that when circadian rhythms and sleep-wake cycles are askew, a wide range of health problems and premature aging are more likely to occur. Clinical evidence demonstrates that individuals with irregular sleep patterns and those that work night shifts and/or get jet lag from traveling may benefit from melatonin supplementation Melatonin may also be useful for those who have trouble falling and staying asleep at night.* Furthermore, melatonin is a potent antioxidant with immune-supporting properties, particularly in
those that are undergoing chemotherapy.* Antioxidants are molecules that reduce oxidative stress
induced by reactive oxygen species in the body.*

Melatonin Dosing Recommendations
To support healthy sleep patterns, take one serving of Melatonin Pro, Melatonin TR Pro, or Melatonin Liquid, one hour before bedtime, or as directed by your healthcare practitioner. *

If you are nursing, pregnant, or taking medications, consult your healthcare practitioner before use.

Zinc plays an important role in supporting the body's natural defense system, as well as nutrient utilization. It is a constituent of over two dozen enzymes involved in digestion and metabolism, including carbonic anhydrase, which is vital to tissue respiration. Zinc is essential for the healthy storage and metabolism of carbohydrates, as well as the absorption and function of B vitamins. Zinc plays a fundamental role in collagen formation and healthy tissue development. This mineral contributes to healthy prostatic function, and is essential for normal fetal and reproductive development.‡

• Supports immune system function‡
• Supports reproductive health‡
• Made with hypoallergenic, vegan ingredients

Zinc is designed to support the body's natural defense system as well as enhance digestion and metabolism of important vitamins, minerals, carbohydrates and other essential nutrients.‡

Quercetin-Ascorbate powder is a powerful flavonoid and antioxidant blend that provides 500 mg of vitamin C (as ascorbic acid) and 500 mg of quercetin in each 1 g serving. Vitamin C works together with bioflavonoids such as quercetin to help promote normal histamine and healthy inflammatory responses.*

Vitamin D3 (Vegan) liquid is a plant-based formula that is made from sustainably harvested lichen. Vitamin D3 provides the body with a wide range of nutritional benefits, including bone, breast, prostate, cardiovascular, colon and immune health.

Pure Encapsulations' Vitamin D3 (Vegan) liquid is derived from naturally occurring, sustainably harvested lichen. It is produced through a multistep process involving extraction, purification and concentration resulting in a vitamin D3 cholecalciferol with the same molecular structure and conformation as cholecalciferol derived from lanolin or fish. It is the only plant-derived source of vitamin D3 that has been accepted by the UK Vegan Society.

Lichen-derived, vegan vitamin D3 to support bone, breast, prostate, cardiovascular, colon and immune health in a convenient liquid form

• Supports bone, prostate and colon functionality
• Promotes cardiovascular and immune health
• Made with hypoallergenic, vegan ingredients
• Convenient, great-tasting liquid formula for easy dispensing

Buffered ascorbic acid combines calcium ascorbate, magnesium ascorbate, and potassium ascorbate to create a neutral pH vitamin C. This special form of ascorbic acid lessens possible gastric irritation in sensitive individuals. Vitamin C is an antioxidant and free radical scavenger with a wide range of functions.  It supports the body's defense system by promoting white blood cell function and activity, interferon levels, antibody responses, and secretion of thymic hormones. It is also essential for the formation and maintenance of intercellular ground substance and collagen. Vitamin C aids in the absorption of iron, the formation of red blood cells and conversion of folic acid to active folinic acid. It also maintains healthy mast cell function and supports lymphocyte formation. Vitamin C is also required for the synthesis of carnitine and steroids.*

• Antioxidant support for cellular health*
• Supports the body's defense systems by promoting white blood cell function and antibody response*
• Provides reduced gastric irritation for sensitive individuals*
• Assists in iron absorption*
• Promotes collagen formation*
• Buffered ascorbic acid with minerals to create aneutral pH vitamin C
• Made with high-quality vegan ingredients backed by verifiable science